{"product_id":"nad-supplement-for-women","title":"NAD+ for Women 45+ – Resveratrol \u0026 Quercetin, Menopause Support","description":"\u003cp\u003eThis NAD+ supplement for women is built for the years when energy and focus stop behaving the way they used to. Each two-capsule serving gives you 500mg of NAD+ (Nicotinamide Adenine Dinucleotide), 250mg of Quercetin Dihydrate, and 150mg of Japanese Knotweed extract standardized to 98% resveratrol, which works out to about 147mg of resveratrol a day. That last number is the reason this page exists. It sits right next to the 150mg daily dose used in a series of clinical trials run specifically in postmenopausal women. It contains no hormones, and it doesn't replace anything your doctor recommends. It's daily menopause support for cellular energy and focus, with the doses printed on the label.\u003c\/p\u003e\n\n\u003ch2\u003eWhy Energy and Focus Change After 45\u003c\/h2\u003e\n\u003cp\u003eTwo things happen at once in midlife, and most women feel them before they can name them.\u003c\/p\u003e\n\u003cp\u003eThe first is NAD+. It's a coenzyme your cells use in more than 500 enzymatic reactions, including making ATP inside your mitochondria. Cleveland Clinic's overview of the research puts the drop at roughly 50% between ages 40 and 60. The second is an enzyme called CD38, whose job is to break NAD+ down. Its activity climbs with age (in adipose tissue, CD38 expression is about 2.5 times higher in older adults than in younger ones). So supply goes down while breakdown goes up.\u003c\/p\u003e\n\u003cp\u003ePerimenopause adds its own layer. Estrogen helps regulate blood flow, including blood flow to the brain, and many women notice the afternoon fog and the dips in stamina around the same time their cycles start to change. A supplement can't undo that transition. What it can do is support the cellular side of your energy while your body adjusts.\u003c\/p\u003e\n\n\u003ch2\u003eThe Resveratrol Dose Studied in Postmenopausal Women\u003c\/h2\u003e\n\u003cp\u003eResearchers at the University of Newcastle in Australia ran the RESHAW trials (Resveratrol for Healthy Ageing in Women) using 75mg of resveratrol twice a day, 150mg daily, in postmenopausal women aged 45 to 85.\u003c\/p\u003e\n\u003cp\u003eIn the 14-week pilot with 80 women, resveratrol increased cerebrovascular responsiveness by 17% compared with placebo and improved verbal memory and overall cognitive performance (Nutrients, 2017). The larger follow-up, 129 women over 12 months, confirmed the improvement in overall cognitive performance (Nutrients, 2020). The same 24-month program also reported better scores for chronic pain, menopause-related quality of life and general well-being (Menopause, 2020), along with small gains in bone density at the lumbar spine and femoral neck (Journal of Bone and Mineral Research, 2020).\u003c\/p\u003e\n\u003cp\u003eTwo honest caveats. Those trials tested resveratrol on its own, not this three-ingredient formula. And this product delivers about 147mg of resveratrol, not exactly 150mg. We think the match is close enough to be worth telling you about, and not close enough to promise you the same results.\u003c\/p\u003e\n\n\u003ch2\u003eWhat Each Ingredient Does in This NAD+ Supplement for Women\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eNAD+ 500mg\u003c\/strong\u003e supplies the coenzyme itself. Part of an oral dose is broken down in the gut into precursors your body can reuse, which is one reason the formula doesn't rely on NAD+ alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuercetin Dihydrate 250mg\u003c\/strong\u003e, from Sophora japonica flower buds, is the most studied natural CD38 inhibitor. A 2013 study in Diabetes measured its CD38 inhibition in cell systems and linked it to higher NAD+ inside cells. In plain terms, it works on the drain rather than the tap.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eResveratrol (98%) from Japanese Knotweed root\u003c\/strong\u003e is included for the reasons above, and because SIRT1, the best known of the sirtuin proteins, can only work when NAD+ is available.\u003c\/p\u003e\n\u003cp\u003eThe capsules are vegetable HPMC. Other ingredients are microcrystalline cellulose, brown rice flour, olive oil, silicon dioxide and magnesium stearate. No artificial colors and no nicotinic acid, so no niacin flush.\u003c\/p\u003e\n\n\u003ch2\u003eHow to Take It\u003c\/h2\u003e\n\u003cp\u003eTake two capsules in the morning with breakfast and a glass of water. Food helps if your stomach is sensitive in the first week or two. Give it at least 30 days before you judge it, and ideally 8 weeks, which is the evaluation window most NAD+ trials use. Consistency matters more than the exact time of day.\u003c\/p\u003e\n\n\u003ch2\u003eTalk to Your Doctor First If This Applies to You\u003c\/h2\u003e\n\u003cp\u003eResveratrol is a phytoestrogen, a plant compound that can interact with estrogen receptors. If you take prescription medication, have a hormone-sensitive or other medical condition, are undergoing medical treatment, or are pregnant or breastfeeding, talk to your doctor before starting.\u003c\/p\u003e\n\n\u003ch2\u003eFrequently Asked Questions\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eIs NAD+ good for women?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNAD+ levels fall with age in both sexes, and most of the people searching for NAD+ support in the US are women between 45 and 64. What's specific to women in this formula is the resveratrol dose, which is the one studied in postmenopausal women.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIs this a menopause treatment?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNo. It's a dietary supplement that supports energy, focus and cellular health during perimenopause and menopause. It isn't intended for any medical condition, and it isn't a substitute for medical care.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow long until I notice a difference?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBlood NAD+ rises within about two weeks in clinical trials. People who notice a change in energy usually describe it somewhere between week 2 and week 4. Give it 8 weeks before deciding.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWill it make me flush?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eNo. Flushing comes from nicotinic acid, and there's none in this formula.\u003c\/p\u003e\n\n\u003cp\u003e\u003cem\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e\n","brand":"Soleu Nutrition","offers":[{"title":"Default Title","offer_id":58610539397451,"sku":"SN-NAD-60C-W","price":49.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1037\/5557\/9723\/files\/NAD_principal.jpg?v=1784498848","url":"https:\/\/soleunutrition.com\/products\/nad-supplement-for-women","provider":"Soleu Nutrition","version":"1.0","type":"link"}